John Krais, who received his Ph.D. in Biomedical Engineering at OU in December of 2015 working with Dr. Roger Harrison, is now a postdoctoral fellow at the Fox Chase Cancer Center in Philadelphia. He is working with Dr. Neil Johnson in the Developmental Therapeutics Program on the study of DNA repair mechanisms and clinically relevant mutations that affect those pathways, with a specific focus on BRCA1 mutations. His aim is to study the impact of the mutant proteins within the cancer cell, investigate mechanisms of acquired resistance to current therapies, and identify potential small molecule therapeutics targeted to DNA repair pathways.
Monday, January 18, 2016
Monday, December 21, 2015
OUBC Professor, Student Published in Journal of Biomedical Sciences
OUBC Ph.D. student, Kat Passlack-Guillen, and Professor, Dr. Roger Harrison and OU-HSC Assistant Professor of Medicine Hematology/Oncology, Carla Kurkjian, were recently published in the Journal of Biomedical Science for their research article entitled, "Targeted enzyme prodrug therapy for metastatic prostate cancer – a comparative study of L-methioninase, purine nucleoside phosphorylase, and cytosine deaminase."
Click here to download the paper (PDF).
Click here to download the paper (PDF).
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